Trial intelligence / Profile preview

BAFF-R CART for Refractory Neuroimmune Diseases

NCT07022197Phase 2Recruiting

Sponsor
Tianjin Medical University General Hospital
Start
Apr 2025
Primary completion
Dec 2027
Modality
CAR-T Cells
Countries
1
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Overview

Phase 2, open-label, single-arm trial of PMB-CT01 in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), Neuromyelitis Optica Spectrum Disorder (NMOSD), myasthenia gravis (MG) and 2 more, sponsored by Tianjin Medical University General Hospital. Primary endpoints: Dose-limiting toxicity at 3 months and Adverse Events at 2 years. Started Apr 2025; status: recruiting.

02

Drugs

PMB-CT01
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Conditions

chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)Neuromyelitis Optica Spectrum Disorder (NMOSD)myasthenia gravis (MG)idiopathic inflammatory myopathy (IIM)multiple sclerosis (MS)

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