Trial intelligence / Profile preview

FORTITUDE-HCM: Ninerafaxstat in Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy

NCT07023614Phase 2Recruiting

Sponsor
Imbria Pharmaceuticals
Start
Oct 2025
Primary completion
Dec 2026
Modality
Small Molecules
Countries
11
01

Overview

Phase 2, randomised, double-blind trial in hypertrophic cardiomyopathy (HCM) comparing Ninerafaxstat 200mg MR BID with Placebo BID (2 arms). Primary endpoint: Kansas City Cardiomyopathy Questionnaire Clinical Summary Score at 12 weeks. Started Oct 2025; status: recruiting.

02

Drugs

ninerafaxstat
03

Conditions

hypertrophic cardiomyopathy (HCM)

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