Trial intelligence / Profile preview

AB821 in Advanced Melanoma and Other Solid Tumors

NCT07027488Phase 1Recruiting

Sponsor
Yale University
Start
Aug 2025
Primary completion
Aug 2027
Modality
Fc-Fusion Proteins
Countries
1
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Overview

Phase 1, open-label, single-arm trial of AB821 in melanoma, non-small cell lung cancer (NSCLC), renal cell carcinoma (RCC) and 3 more, sponsored by Yale University. Primary endpoints: Frequency of Dose-Limiting Toxicities up to 2 years, Frequency of Serious Adverse Events up to 2 years and 5 more. Started Aug 2025; status: recruiting.

02

Drugs

AB821
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Conditions

melanomanon-small cell lung cancer (NSCLC)renal cell carcinoma (RCC)Merkel cell carcinoma (MCC)bladder cancer

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