Trial intelligence / Profile preview

Peds CHAMP1ON

NCT07031765Phase 1Active, not recruiting

Sponsor
University of Florida
Start
Jul 2025
Primary completion
Dec 2030
Modality
Stem Cell Therapies, Monoclonal Antibodies
Countries
1
01

Overview

Phase 1, open-label trial of ex vivo expanded CD34+ hematopoietic stem cells and nivolumab in glioma (2 arms), sponsored by University of Florida. Primary endpoints: Rate of Dose-Limiting Toxicities at 4 weeks and Rate of ability to manufacture a product that meets release specifications and deliver the first study treatment at 4 weeks. Started Jul 2025; status: active, not recruiting.

02

Drugs

ex vivo expanded CD34+ hematopoietic stem cellsnivolumab
03

Conditions

glioma

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