Trial intelligence / Profile preview

TRIFECTA-DARED: Pubertal Induction in Turner Syndrome

NCT07041814Phase 2Not yet recruiting

Sponsor
Hospital Canselor Tuanku Muhriz
Start
Feb 2026
Primary completion
Apr 2029
Countries
1
01

Overview

Phase 2, randomised, open-label trial of estradiol topical in Turner syndrome (TS) (2 arms), sponsored by Hospital Canselor Tuanku Muhriz. Primary endpoints: Proportions of Turner Syndrome with Satisfactory Breast Development (Tanner Breast Stage 3 and above) at 19 months, Median time to achieving Tanner Breast Stage 4 (B4) and above at 19 months and 2 more. Planned start Feb 2026; status: not yet recruiting.

02

Drugs

estradiol topical
03

Conditions

Turner syndrome (TS)

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