Trial intelligence / Profile preview

NALIRIFOX in Advanced Small Intestine and Appendiceal Cancers

NCT07060014Phase 1Recruiting

Sponsor
Houston Methodist Research Institute
Start
Sep 2026
Primary completion
Sep 2028
Modality
Lipid-based Nanoparticles, Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of nanoliposomal irinotecan, fluorouracil, folinic acid and oxaliplatin in small intestine cancer and appendiceal cancer (2 arms), sponsored by Houston Methodist Research Institute. Primary endpoint: Treatment-Related Adverse Events at 12 months. Started Sep 2026; status: recruiting.

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Drugs

nanoliposomal irinotecanfluorouracilfolinic acidoxaliplatin
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Conditions

small intestine cancerappendiceal cancer

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