Trial intelligence / Profile preview

SPT-300 in Major Depressive Disorder

NCT07065240Phase 2Recruiting

Sponsor
Seaport Therapeutics
Start
Jun 2025
Primary completion
Mar 2027
Modality
Prodrugs/Conditional Activator Small Molecules
Countries
7
01

Overview

Phase 2, randomised, double-blind trial in major depressive disorder (MDD) comparing SPT-300 with Placebo (2 arms). Primary endpoint: Hamilton Depression Rating Scale-17 Total Score at 42 days. Started Jun 2025; status: recruiting.

02

Drugs

GlyphAllo
03

Conditions

major depressive disorder (MDD)

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