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Effect of HRS-8427 on Furosemide and Metformin PK
NCT07073157Phase 1Completed
- Sponsor
- Hengrui
- Start
- Jul 2025
- Primary completion
- Aug 2025
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 1, open-label trial of HRS-8427 in complicated urinary tract infection (cUTI) and acute pyelonephritis (2 arms), sponsored by Hengrui. Primary endpoints: Maximum Plasma Concentration at Day 9, Area Under the Curve from time 0 to t at Day 9 and 5 more. Started Jul 2025; status: completed.
02
Drugs
HRS-8427
03
Conditions
complicated urinary tract infection (cUTI)acute pyelonephritis
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