Trial intelligence / Profile preview

ALLO-329 in Autoimmune Disease

NCT07085104Phase 1Recruiting

Sponsor
Allogene Therapeutics
Start
Nov 2025
Primary completion
Feb 2028
Modality
CRISPR-Cas9, CAR-T Cells
Countries
2
01

Overview

Phase 1, open-label trial of ALLO-329 in systemic lupus erythematosus (SLE), idiopathic inflammatory myopathy (IIM) and systemic sclerosis (SSc) (3 arms), sponsored by Allogene Therapeutics. Primary endpoint: Incidence of Dose Limiting toxicities (DLTs) and Other Safety Parameters at 60 months. Started Nov 2025; status: recruiting.

02

Drugs

ALLO-329
03

Conditions

systemic lupus erythematosus (SLE)idiopathic inflammatory myopathy (IIM)systemic sclerosis (SSc)

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