Trial intelligence / Profile preview

pTVG-HP and Nivolumab in Non-Castrate Recurrent Oligometastatic Prostate Cancer

NCT07090148Phase 1Recruiting

Sponsor
University of Wisconsin–Madison
Start
Mar 2026
Primary completion
Oct 2030
Modality
Prophylactic Vaccines, DNA Vaccines
Countries
1
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Overview

Phase 1, open-label, single-arm trial of pTVG-HP plasmid DNA vaccine in prostate cancer (PCa), sponsored by University of Wisconsin–Madison. Primary endpoints: Prostate-Specific Antigen Complete Response Rate at 12 months, Incidence of Adverse Events at 5 years and 1 more. Started Mar 2026; status: recruiting.

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Drugs

pTVG-HP plasmid DNA vaccine
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Conditions

prostate cancer (PCa)

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