Trial intelligence / Profile preview

Sevabertinib in Hepatic Impairment

NCT07102095Phase 1Completed

Sponsor
Bayer
Start
Jul 2025
Primary completion
Dec 2025
Modality
Fragment-Derived Small Molecules, Allosteric Modulators, Orthosteric Ligands
Countries
1
01

Overview

Phase 1, open-label trial of sevabertinib in cancer, lung cancer and metastatic cancer (2 arms), sponsored by Bayer. Primary endpoints: Area under plasma concentration-time curve, Unbound area under plasma concentration-time curve and 2 more. Started Jul 2025; status: completed.

02

Drugs

sevabertinib
03

Conditions

cancerlung cancermetastatic cancer

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