Trial intelligence / Profile preview

Anti-human CD7 CAR-NK in Relapsed/Refractory CD7+ Hematological Malignancies

NCT07117175Phase 1Not yet recruiting

Sponsor
Shanghai General Hospital
Start
Sep 2025
Primary completion
Dec 2027
Modality
Lymphokine-Activated Killer Cells, CAR-NK Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of anti-human CD7 CAR-NK cell in acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LL), sponsored by Shanghai General Hospital. Primary endpoints: Incidence of dose-limiting toxicity at 28 days and Incidence of adverse events at 2 years. Planned start Sep 2025; status: not yet recruiting.

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Drugs

anti-human CD7 CAR-NK cell
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Conditions

acute myeloid leukemia (AML)acute lymphoblastic leukemia (ALL)lymphoblastic lymphoma (LL)

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