Trial intelligence / Profile preview

Phase 1 SAD/MAD Study of BIIB142 in Healthy Adults

NCT07133828Phase 1Recruiting

Sponsor
Biogen
Start
Aug 2025
Primary completion
Aug 2026
Modality
Bivalent/Multivalent Binders, PROTACs (E3 ligase recruitment)
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of BIIB142 (9 cohorts), sponsored by Biogen. Primary endpoints: Number of Participants With Treatment Emergent Adverse Events (TEAEs) and Serious Adverse Events (SAEs), Number of Participants with Clinical Laboratory Abnormalities and 3 more. Started Aug 2025; status: recruiting.

02

Drugs

BIIB142

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