Trial intelligence / Profile preview

DB-1317 in Advanced/Metastatic Solid Tumors

NCT07141706Phase 1Recruiting

Sponsor
Duality Biotherapeutics
Start
Sep 2025
Primary completion
Jun 2028
Modality
Antibody-Drug Conjugates (ADCs)
Countries
3
01

Overview

Phase 1, randomised, open-label trial of DB-1317 in solid tumor, gastric cancer (GC), colorectal cancer (CRC) and 1 more (9 arms), sponsored by Duality Biotherapeutics. Primary endpoints: Dose-Limiting Toxicities at 21 days, Treatment Emergent Adverse Events at 1 year and 7 more. Started Sep 2025; status: recruiting.

02

Drugs

DB-1317
03

Conditions

solid tumorgastric cancer (GC)colorectal cancer (CRC)pancreatic ductal adenocarcinoma (PDAC)

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