Trial intelligence / Profile preview

GOAL-Stop: Stopping Penicillin in Early Rheumatic Heart Disease

NCT07146048Phase 3Recruiting

Sponsor
Cincinnati Children's Hospital Medical Center
Start
Mar 2026
Primary completion
Feb 2029
Modality
Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of benzylpenicillin in rheumatic heart disease (RHD) (2 arms), sponsored by Cincinnati Children's Hospital Medical Center. Primary endpoint: Presence of echocardiographic progression of RHD at 2 years. Started Mar 2026; status: recruiting.

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Drugs

benzylpenicillin
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Conditions

rheumatic heart disease (RHD)

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