Trial intelligence / Profile preview

SKYWAY-RD: SPY002-072 in Rheumatologic Disease

NCT07148414Phase 2Active, not recruiting

Sponsor
Spyre Therapeutics, Inc.
Start
Aug 2025
Primary completion
Oct 2026
Modality
Engineered Antibody Formats, Antibody Conjugates, Monoclonal Antibodies
Countries
8
01

Overview

Phase 2, randomised, double-blind trial of SPY002 in rheumatoid arthritis (RA), axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) (7 arms), sponsored by Spyre Therapeutics, Inc. Primary endpoints: Disease Activity Score in 28 joints (c-reactive protein) at 12 weeks, Ankylosing Spondylitis Disease Activity Score at 16 weeks and 1 more. Started Aug 2025; status: active, not recruiting.

02

Drugs

SPY002
03

Conditions

rheumatoid arthritis (RA)axial spondyloarthritis (axSpA)psoriatic arthritis (PsA)

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