Trial intelligence / Profile preview

Vorinostat in Pitt Hopkins Syndrome

NCT07150026Phase 1Recruiting

Sponsor
Unravel Biosciences
Start
Mar 2026
Primary completion
Dec 2026
Modality
Covalent Small Molecules, Classical Binding Small Molecules
Countries
1
01

Overview

Phase 1, single-blind trial of vorinostat in Pitt-Hopkins syndrome (PTHS) (3 arms), sponsored by Unravel Biosciences. Primary endpoints: Frequency of treatment-related adverse events at 20 weeks, Drug tolerability as measured by number of treatment discontinuations at 20 weeks and 1 more. Started Mar 2026; status: recruiting.

02

Drugs

vorinostat
03

Conditions

Pitt-Hopkins syndrome (PTHS)

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