Trial intelligence / Profile preview

Pozelimab and Cemdisiran Combination Therapy in PNH

NCT07154745Phase 3Recruiting

Sponsor
Regeneron Pharmaceuticals
Start
Jun 2026
Primary completion
Jan 2030
Modality
Antisense DNA, Recombinant Proteins and Enzymes, Conjugated siRNA
Countries
7
01

Overview

Phase 3, open-label, single-arm trial of pozelimab and cemdisiran in paroxysmal nocturnal hemoglobinuria (PNH), sponsored by Regeneron Pharmaceuticals. Primary endpoint: Percent change in Lactate Dehydrogenase at 28 weeks. Started Jun 2026; status: recruiting.

02

Drugs

pozelimabcemdisiran
03

Conditions

paroxysmal nocturnal hemoglobinuria (PNH)

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