Trial intelligence / Profile preview

Maridebart Cafraglutide in Type 2 Diabetes Mellitus

NCT07160257Phase 1Active, not recruiting

Sponsor
Amgen
Start
Aug 2025
Primary completion
Nov 2026
Modality
Peptides, Monoclonal Antibodies
Countries
1
01

Overview

Phase 1, randomised, double-blind trial in type 2 diabetes mellitus (T2DM) comparing Maridebart cafraglutide with Placebo (2 arms). Primary endpoint: Change from Baseline in M-value from Hyperinsulinemic-euglycemic Clamp at 25 weeks. Started Aug 2025; status: active, not recruiting.

02

Drugs

maridebart cafraglutide
03

Conditions

type 2 diabetes mellitus (T2DM)

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