Trial intelligence / Profile preview

Anti-CD19 CAR T Cells With HLA-Haploidentical HCT for High-Risk Blood Cancers

NCT07162038Phase 1Recruiting

Sponsor
National Cancer Institute
Start
Nov 2025
Primary completion
Nov 2030
Modality
CAR-T Cells
Countries
1
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Overview

Phase 1, open-label trial of anti-CD19 CAR-T cells in hematologic malignancy (3 arms), sponsored by National Cancer Institute. Primary endpoints: Safety of anti-CD19 CAR T-cell therapy in combination with HLA-haploidentical HCT at 28 days and 1 year relapse and survival outcomes at the maximum tolerated dose. Started Nov 2025; status: recruiting.

02

Drugs

anti-CD19 CAR-T cells
03

Conditions

hematologic malignancy

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