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Effect of Rabeprazole or Famotidine on the Pharmacokinetics of Nirogacestat in Healthy Adult Male Participants
NCT07171619Phase 1Completed
- Sponsor
- SpringWorks Therapeutics
- Start
- Aug 2025
- Primary completion
- Nov 2025
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 1, open-label trial of nirogacestat in desmoid fibromatosis (DF) (3 arms), sponsored by SpringWorks Therapeutics. Primary endpoints: Area under the concentration-time curve from time zero to infinity and Maximum serum concentration. Started Aug 2025; status: completed.
02
Drugs
nirogacestat
03
Conditions
desmoid fibromatosis (DF)
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