Trial intelligence / Profile preview

JSB462 in Japanese Patients With Metastatic Prostate Cancer

NCT07174063Phase 1Active, not recruiting

Sponsor
Novartis
Start
Nov 2025
Primary completion
Jan 2027
Modality
Bivalent/Multivalent Binders, PROTACs (E3 ligase recruitment)
Countries
1
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Overview

Phase 1, open-label, single-arm trial of luxdegalutamide in metastatic castration-resistant prostate cancer (mCRPC), sponsored by Novartis. Primary endpoints: Dose Limiting Toxicities at 28 days, Adverse Events and Serious Adverse Events at 18 months and 6 more. Started Nov 2025; status: active, not recruiting.

02

Drugs

luxdegalutamide
03

Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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