Trial intelligence / Profile preview

CD70-Targeted CAR-T in Advanced CD70-Positive Malignant Solid Tumors

NCT07181720Phase 1Suspended

Sponsor
Chongqing Precision Biotech
Start
Sep 2025
Primary completion
Mar 2028
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
01

Overview

Phase 1, open-label trial of CD70 CAR-T cells in renal cell carcinoma (RCC), lung cancer, anaplastic thyroid carcinoma (ATC) and 3 more (3 arms), sponsored by Chongqing Precision Biotech. Primary endpoints: Safety and Tolerability at 1 month and Recommended dose and infusion regimen at 1 month. Started Sep 2025; status: suspended.

02

Drugs

CD70 CAR-T cells
03

Conditions

renal cell carcinoma (RCC)lung canceranaplastic thyroid carcinoma (ATC)ovarian cancerCervical Cancer (CC)

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