Trial intelligence / Profile preview

Fast TILs in Metastatic Cancer With Pleural Disease

NCT07192900Phase 1Recruiting

Start
Jun 2026
Primary completion
Apr 2033
Modality
Monoclonal Antibodies, Cell Therapies
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of GC101 TIL + pembrolizumab in malignant pleural effusion (MPE), malignant mesothelioma and Secondary malignant neoplasm of pleura. Primary endpoints: Feasibility of local manufacture of ACT product from drained pleural effusions using the CliniMACS Prodigy device at 30 days and Safety of intrapleural administration of the locally manufactured ACT product plus Interleukin 2 (IL-2) at 5 years. Started Jun 2026; status: recruiting.

02

Drugs

GC101 TIL + pembrolizumab
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Conditions

malignant pleural effusion (MPE)malignant mesotheliomaSecondary malignant neoplasm of pleura

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