Trial intelligence / Profile preview

GDC-0587 Monotherapy and Combination With Giredestrant in ER+/HER2- Breast Cancer

NCT07214662Phase 1Terminated

Sponsor
Genentech
Start
Jan 2026
Primary completion
Jun 2026
Modality
Small Molecules
Countries
2
01

Overview

Phase 1, open-label trial of RGT-587 in breast cancer (3 arms), sponsored by Genentech. Primary endpoints: Percentage of Participants with Adverse Events up to 18 months and Percentage of Participants with Dose-limiting Toxicity at 28 days. Started Jan 2026; status: terminated.

02

Drugs

RGT-587
03

Conditions

breast cancer

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