Trial intelligence / Profile preview

Pharmacokinetics of MK-1084 in Participants With Hepatic Impairment

NCT07219550Phase 1Completed

Sponsor
Merck & Co.
Start
Nov 2025
Primary completion
Jul 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of calderasib in cancer, sponsored by Merck & Co. Primary endpoints: Area Under the Concentration Versus Time Curve from 0 to the Time of the Last Quantifiable Sample at 7 days, Area Under the Concentration Versus Time Curve from 0 to Infinity at 7 days and 6 more. Started Nov 2025; status: completed.

02

Drugs

calderasib
03

Conditions

cancer

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