Trial intelligence / Profile preview

NEPHRON: Finerenone vs FDC of ER Torsemide and Spironolactone in Hypertension and CKD

NCT07223502Phase 3Withdrawn

Start
May 2025
Primary completion
Sep 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 3, randomised trial of torasemide and spironolactone in hypertension (HTN) and chronic kidney disease (CKD) (2 arms). Primary endpoints: Net Clinical Benefit (NBC) with Systolic Blood Pressure reduction at 12 weeks, Net Clinical Benefit (NBC) with Urine Albumin-to-Creatinine Ratio reduction at 12 weeks and 1 more. Planned start May 2025; status: withdrawn.

02

Drugs

torasemidespironolactone
03

Conditions

hypertension (HTN)chronic kidney disease (CKD)

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