Trial intelligence / Profile preview

Repotrectinib DDI Study in Healthy Adults

NCT07223671Phase 1Completed

Sponsor
Bristol Myers Squibb
Start
Dec 2025
Primary completion
Feb 2026
Modality
Fragment-Derived Small Molecules, Allosteric Modulators, Orthosteric Ligands
Countries
1
01

Overview

Phase 1, open-label trial of repotrectinib in non-small cell lung cancer (NSCLC) and solid tumor (2 cohorts), sponsored by Bristol Myers Squibb. Primary endpoints: Area Under the Plasma Concentration-time Curve From Time Zero to Time of Last Quantifiable Concentration at Day 17, Area Under the Plasma Concentration-time Curve From Time Zero Extrapolated to Infinite Time at Day 17 and 3 more. Started Dec 2025; status: completed.

02

Drugs

repotrectinib
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Conditions

non-small cell lung cancer (NSCLC)solid tumor

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