Trial intelligence / Profile preview

RO7812653 in Early Symptomatic Alzheimer's Disease

NCT07234942Phase 1Active, not recruiting

Sponsor
Roche
Start
Jan 2026
Primary completion
Mar 2027
Modality
Modified DNA Oligonucleotides, Single-strand DNA, Antisense Oligonucleotides (ASOs)
Countries
5
01

Overview

Phase 1, randomised, double-blind trial in Alzheimer's disease (AD) comparing RO7812653 with Placebo (2 arms). Primary endpoints: Adverse Events at 40 weeks and Columbia-Suicide Severity Rating Scale at 40 weeks. Started Jan 2026; status: active, not recruiting.

02

Drugs

RO7812653
03

Conditions

Alzheimer's disease (AD)

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