Trial intelligence / Profile preview

ZVS106e in ABCA4-mutated Hereditary Retinal Degeneration (Stargardt Disease)

NCT07241169Phase 1Recruiting

Sponsor
Zhongshan Ophthalmic Center
Start
Dec 2025
Primary completion
Nov 2028
Modality
Gene Editing, Gene Silencing, Gene Addition/Replacement
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of ZVS106e in Stargardt disease (STGD), sponsored by Zhongshan Ophthalmic Center. Primary endpoint: Safety and tolerability of subretinal injection of ZVS106e solution at 52 weeks. Started Dec 2025; status: recruiting.

02

Drugs

ZVS106e
03

Conditions

Stargardt disease (STGD)

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