Trial intelligence / Profile preview

Zanidatamab + Tislelizumab in HER2+ GI Tumors

NCT07243938Phase 2Not yet recruiting

Start
Jan 2026
Primary completion
Jul 2028
Modality
Bispecific Antibodies, Monoclonal Antibodies
01

Overview

Phase 2, open-label trial of zanidatamab in rectal cancer, gastric cancer (GC), gastroesophageal junction cancer and 1 more (3 cohorts). Primary endpoints: Complete Response Rate at 18 weeks, Pathological Complete Response Rate at 15 weeks and 1 more. Planned start Jan 2026; status: not yet recruiting.

02

Drugs

zanidatamab
03

Conditions

rectal cancergastric cancer (GC)gastroesophageal junction cancercolorectal cancer (CRC)

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