Trial intelligence / Profile preview

Subanesthetic-dose Esketamine in Modified Electroconvulsive Therapy for Adolescents With Severe Depression

NCT07247968Phase 1Recruiting

Start
Nov 2025
Primary completion
Nov 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial in major depressive disorder (MDD) comparing Esketamine + MECT with Placebo + MECT (2 arms). Primary endpoint: Treatment response rate of depressive symptoms. Started Nov 2025; status: recruiting.

02

Drugs

esketamine
03

Conditions

major depressive disorder (MDD)

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