Trial intelligence / Profile preview

Pharmacokinetics and Safety of BMS-986435 in Hepatic Impairment

NCT07248839Phase 1Completed

Sponsor
Bristol Myers Squibb
Start
Dec 2025
Primary completion
Aug 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of BMS-986435 in hypertrophic cardiomyopathy (HCM) (3 arms), sponsored by Bristol Myers Squibb. Primary endpoints: Maximum observed concentration at Day 45, Area under the concentration-time curve from time zero to time of last quantifiable concentration at Day 45 and 1 more. Started Dec 2025; status: completed.

02

Drugs

BMS-986435
03

Conditions

hypertrophic cardiomyopathy (HCM)

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