Trial intelligence / Profile preview

KEYMAKER-U01 Substudy 01J: MK-1084 in First-line KRAS G12C-mutated NSCLC

NCT07252739Phase 2Recruiting

Sponsor
Merck & Co.
Start
Dec 2025
Primary completion
Nov 2029
Modality
Small Molecules
Countries
13
01

Overview

Phase 2, randomised, open-label trial of calderasib in non-small cell lung cancer (NSCLC) (3 arms), sponsored by Merck & Co. Primary endpoints: Dose Limiting Toxicity at 21 days, Adverse Events at 84 months and 2 more. Started Dec 2025; status: recruiting.

02

Drugs

calderasib
03

Conditions

non-small cell lung cancer (NSCLC)

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