Trial intelligence / Profile preview

Nicotinamide in Leber's Hereditary Optic Neuropathy

NCT07258667Phase 1Not yet recruiting

Sponsor
Centre Hospitalier Universitaire d'Angers
Start
Apr 2026
Primary completion
Apr 2028
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of nicotinamide in Leber hereditary optic neuropathy (LHON), sponsored by Centre Hospitalier Universitaire d'Angers. Primary endpoint: Efficacy of administering 2 grams per day of nicotinamide at 12 months. Planned start Apr 2026; status: not yet recruiting.

02

Drugs

nicotinamide
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Conditions

Leber hereditary optic neuropathy (LHON)

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