Trial intelligence / Profile preview

177Lu-DFC413 and 68Ga-NNS309 in Solid Tumors

NCT07261631Phase 1Recruiting

Sponsor
Novartis
Start
Nov 2025
Primary completion
May 2029
Modality
Radiopharmaceutical
Countries
7
01

Overview

Phase 1, open-label, single-arm trial of 177Lu-DFC413 in pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), breast cancer and 3 more, sponsored by Novartis. Primary endpoints: Dose Limiting Toxicities at 6 weeks, Adverse Events and Serious Adverse Events at 42 months and 2 more. Started Nov 2025; status: recruiting.

02

Drugs

177Lu-DFC413
03

Conditions

pancreatic ductal adenocarcinoma (PDAC)non-small cell lung cancer (NSCLC)breast cancertriple-negative breast cancer (TNBC)colorectal cancer (CRC)

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