Trial intelligence / Profile preview

BioTTT001 in Recurrent/Progressive NSCLC with Meningeal Metastasis

NCT07264569Phase 2Recruiting

Sponsor
Henan Cancer Hospital
Start
Jun 2025
Primary completion
Dec 2027
Modality
Oncolytic Viruses
Countries
1
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Overview

Phase 2, open-label, single-arm trial of BioTTT001 in non-small cell lung cancer (NSCLC) and leptomeningeal metastasis (LMD), sponsored by Henan Cancer Hospital. Primary endpoints: Dose-Limiting Toxicity, Maximum Tolerated Dose, and Recommended Phase 2 Dose and Phase Ib dose-escalation study safety at 28 days. Started Jun 2025; status: recruiting.

02

Drugs

BioTTT001
03

Conditions

non-small cell lung cancer (NSCLC)leptomeningeal metastasis (LMD)

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