Trial intelligence / Profile preview

CNCT19 in Relapsed or Refractory Autoimmune Neurological Diseases

NCT07275736Phase 1Recruiting

Sponsor
Juventas Cell Therapy Ltd.
Start
Mar 2025
Primary completion
Jun 2027
Modality
CAR-T Cells
Countries
1
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Overview

Phase 1, open-label trial of inaticabtagene autoleucel in Neuromyelitis Optica Spectrum Disorder (NMOSD), myasthenia gravis (MG), Chronic inflammatory demyelinating polyradiculopathy (CIDP) and 3 more, sponsored by Juventas Cell Therapy Ltd. Primary endpoints: Number of participants with dose-limiting toxicities at 28 days and Number of participants with adverse events/serious adverse events at 36 months. Started Mar 2025; status: recruiting.

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Drugs

inaticabtagene autoleucel
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Conditions

Neuromyelitis Optica Spectrum Disorder (NMOSD)myasthenia gravis (MG)Chronic inflammatory demyelinating polyradiculopathy (CIDP)multiple sclerosis (MS)Autoimmune Encephalitis (AE)

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