Trial intelligence / Profile preview

Amivantamab plus Pembrolizumab and Carboplatin in Treatment-Naïve Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

NCT07276399Phase 3Recruiting

Sponsor
Janssen Pharmaceutical
Start
Dec 2025
Primary completion
Jun 2029
Modality
Bispecific Antibodies, Monoclonal Antibodies
Countries
22
01

Overview

Phase 3, randomised, open-label trial of amivantamab in head and neck squamous cell carcinoma (HNSCC) (2 arms), sponsored by Janssen Pharmaceutical. Primary endpoints: Overall Survival and Objective Response Rate. Started Dec 2025; status: recruiting.

02

Drugs

amivantamab
03

Conditions

head and neck squamous cell carcinoma (HNSCC)

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