Trial intelligence / Profile preview

IDE892 as Monotherapy and Combination Therapy in MTAP-Deleted Advanced Solid Tumors

NCT07277413Phase 1Recruiting

Sponsor
IDEAYA Biosciences
Start
Mar 2026
Primary completion
Apr 2028
Modality
Orthosteric Ligands
Countries
1
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Overview

Phase 1, open-label trial of IDE892 in solid tumor, non-small cell lung cancer (NSCLC), gastroesophageal junction cancer and 4 more (4 arms), sponsored by IDEAYA Biosciences. Primary endpoints: Dose-limiting Toxicities at 21 days, Adverse Events and Serious Adverse Events and 2 more. Started Mar 2026; status: recruiting.

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Drugs

IDE892
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Conditions

solid tumornon-small cell lung cancer (NSCLC)gastroesophageal junction cancerurothelial carcinoma (UC)mesothelioma

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