Trial intelligence / Profile preview

VX-581 in Healthy Subjects and Cystic Fibrosis

NCT07283770Phase 1Recruiting

Sponsor
Vertex Pharmaceuticals
Start
Dec 2025
Primary completion
Jul 2027
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of VX-581 in cystic fibrosis (CF) (7 arms), sponsored by Vertex Pharmaceuticals. Primary endpoint: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs) at Day 105. Started Dec 2025; status: recruiting.

02

Drugs

VX-581
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Conditions

cystic fibrosis (CF)

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