Trial intelligence / Profile preview

MTX-474 in Diffuse Cutaneous Systemic Sclerosis

NCT07287670Phase 2Recruiting

Sponsor
Mediar Therapeutics
Start
Apr 2026
Primary completion
Dec 2028
Modality
Monoclonal Antibodies, Orthosteric Ligands
Countries
10
01

Overview

Phase 2, randomised, double-blind trial in diffuse cutaneous systemic sclerosis (dcSSc) comparing MTX-474 with Placebo (2 arms). Primary endpoint: Modified Rodnan Skin Score at 24 weeks. Started Apr 2026; status: recruiting.

02

Drugs

MTX-474
03

Conditions

diffuse cutaneous systemic sclerosis (dcSSc)

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