Trial intelligence / Profile preview

anti-PSMA CAR-NK in mCRPC

NCT07298239Phase 1Recruiting

Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Start
Dec 2025
Primary completion
Apr 2028
Modality
Lymphokine-Activated Killer Cells, CAR-NK Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of anti-PSMA CAR-NK cells (CIH-CAMS) in metastatic castration-resistant prostate cancer (mCRPC), sponsored by Cancer Institute and Hospital, Chinese Academy of Medical Sciences. Primary endpoint: Occurrence of treatment related adverse events as assessed by CTCAE v5.0 at 1 year. Started Dec 2025; status: recruiting.

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Drugs

anti-PSMA CAR-NK cells (CIH-CAMS)
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Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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