Trial intelligence / Profile preview

PCV +/- AB248 in Triple Negative Breast Cancer

NCT07300475Phase 1Not yet recruiting

Sponsor
Washington University School of Medicine
Start
Dec 2026
Primary completion
Sep 2030
Modality
Fc-Fusion Proteins
Countries
1
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Overview

Phase 1, randomised, open-label trial of personalized neoantigen vaccine (UC San Diego) and etakafusp alfa in triple-negative breast cancer (TNBC) (2 arms), sponsored by Washington University School of Medicine. Primary endpoints: Treatment-emergent adverse events at 115 days, Treatment-related adverse events at 115 days and 4 more. Planned start Dec 2026; status: not yet recruiting.

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Drugs

personalized neoantigen vaccine (UC San Diego)etakafusp alfa
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Conditions

triple-negative breast cancer (TNBC)

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