Trial intelligence / Profile preview

Effect of MK-8507 on the QTc Interval in Healthy Adult Participants

NCT07305831Phase 1Completed

Sponsor
Merck & Co.
Start
Jan 2026
Primary completion
Apr 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial in human immunodeficiency virus type 1 infection (HIV-1) comparing Moxifloxacin 400 mg + Placebo with Ulonivirine Dose 1 + Placebo (2 arms). Primary endpoints: Change From Baseline in QT Interval Corrected for Heart Rate (QTc) Following Ulonivirine Administration up to 24 hours and Plasma Concentration of Ulonivirine at QTc Intervals (Cqtc) up to 24 hours. Started Jan 2026; status: completed.

02

Drugs

ulonivirine
03

Conditions

human immunodeficiency virus type 1 infection (HIV-1)

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