Trial intelligence / Profile preview

ASCEND-CRC in Metastatic Colorectal Cancer

NCT07318389Phase 1Recruiting

Sponsor
University of Texas MD Anderson Cancer Center
Start
Apr 2026
Primary completion
Nov 2027
Modality
Monoclonal Antibodies, Antibody-Drug Conjugates (ADCs), Engineered Antibody Formats
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of bevacizumab, KL-140, panitumumab, FOLFIRI, FOLFOX and 6 more in colorectal cancer (CRC), sponsored by University of Texas MD Anderson Cancer Center. Primary endpoint: Safety and Adverse Events at 1 year. Started Apr 2026; status: recruiting.

02

Drugs

bevacizumabKL-140panitumumabFOLFIRIFOLFOX
03

Conditions

colorectal cancer (CRC)

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