Trial intelligence / Profile preview

DNL628 in Early Alzheimer's Disease

NCT07328451Phase 1Recruiting

Sponsor
Denali Therapeutics Inc.
Start
Jan 2026
Primary completion
Feb 2027
Modality
Modified DNA Oligonucleotides, Single-strand DNA, Antisense Oligonucleotides (ASOs)
Countries
2
01

Overview

Phase 1, randomised, double-blind trial of DNL628 in Alzheimer's disease (AD) (2 arms), sponsored by Denali Therapeutics Inc. Primary endpoint: Treatment-Emergent Adverse Events at 37 weeks. Started Jan 2026; status: recruiting.

02

Drugs

DNL628
03

Conditions

Alzheimer's disease (AD)

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