Trial intelligence / Profile preview

LUCAR-G79D in r/r SLE and r/r IIM

NCT07331272Phase 1Recruiting

Sponsor
Legend Biotech Corporation
Start
Jan 2026
Primary completion
Jan 2028
Modality
CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of LUCAR-G79D in systemic lupus erythematosus (SLE) and idiopathic inflammatory myopathy (IIM), sponsored by Legend Biotech Corporation. Primary endpoints: Treatment-Emergent Adverse Events at 104 weeks, Dose-Limiting Toxicity at 104 weeks and 4 more. Started Jan 2026; status: recruiting.

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Drugs

LUCAR-G79D
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Conditions

systemic lupus erythematosus (SLE)idiopathic inflammatory myopathy (IIM)

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