Trial intelligence / Profile preview

Phase 1 Study of h20.19 CAR T Cells in Relapsed/Refractory B Cell Malignancies

NCT07335328Phase 1Not yet recruiting

Sponsor
Medical College of Wisconsin
Start
Nov 2026
Primary completion
May 2027
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
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Overview

Phase 1, open-label trial of h20.19 CAR T cells in B-cell non-Hodgkin lymphoma, chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL) and 2 more (3 arms), sponsored by Medical College of Wisconsin. Primary endpoint: Maximum Tolerated Dose at 28 days. Planned start Nov 2026; status: not yet recruiting.

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Drugs

h20.19 CAR T cells
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Conditions

B-cell non-Hodgkin lymphomachronic lymphocytic leukemia (CLL)mantle cell lymphoma (MCL)diffuse large B-cell lymphoma (DLBCL)small lymphocytic lymphoma (SLL)

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