Trial intelligence / Profile preview

huCART19-IL18-eDHFR in Relapsed or Refractory Follicular Lymphoma

NCT07343934Phase 1Recruiting

Sponsor
University of Pennsylvania
Start
May 2026
Primary completion
Nov 2027
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
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Overview

Phase 1, open-label trial of huCART19-IL18-eDHFR in follicular lymphoma (FL) (2 arms), sponsored by University of Pennsylvania. Primary endpoint: Change in Tumor Uptake on [18F]FP-TMP PET/CT at 6 months. Started May 2026; status: recruiting.

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Drugs

huCART19-IL18-eDHFR
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Conditions

follicular lymphoma (FL)

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